Now this is an exiting breakthrough in the understanding of pain.
"This is a major breakthrough in understanding the mechanisms of pain and how to more effectively treat it," Dr. Hargreaves said. "These data demonstrate, for the first time, that OLAMs constitute a new family of naturally occurring capsaicin-like agents, and may explain the role of these substances in many pain conditions. This hypothesis suggests that agents blocking either the production or action of these substances could lead to new therapies and pharmacological interventions for various inflammatory diseases and pain disorders such as arthritis, fibromyalgia and others, including pain associated with cancer."
OLAMs are oxidized linoleic acid metabolites which are created from cells at the source of the pain. These are similar to the capsaicin oil that is found in chili peppers. So if you block these molecules then you might be able to block the pain right at the source instead of in the brain like opioids.
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