Monday, January 12, 2015

MS Treatment might Stop the Progression of the Disease

This seems pretty encouraging if you have MS.
The procedures, abbreviated as HDIT and HCT, are the focus of the multicenter trial that includes experts from seven U.S. states, plus Canada and England.
A three-year interim report published recently in the journal JAMA Neurology offered positive results: Nearly 80 percent of those enrolled, including Kearny, not only survived but also showed no increase in disability, relapse of MS symptoms or new brain lesions. Few serious complications or unexpected side effects were reported. 
That is pretty stunning news because 80% chance of stopping the disease in its tracks sounds outstanding. What is interesting is that the mechanism seems to be what you use to get rid of lueukimia
The trial patients all had failed standard treatments for MS in the 18 months before they enrolled; typically they’d exhausted three different lines of care, said Dr. Richard Nash of the Colorado Blood Cancer Institute.
They received high doses of drugs to wipe out their immune systems and then doses of their own stem cells to rebuild them.
It’s a technique first pioneered for to the now-common treatment for leukemia and other cancers.
This kind of sounds like CAR-T Immunotherapy but you use stem cells instead of specially engineered T-Cells. I guess your body uses the new stem cells to recreate the immune system without creating the lesions in the brain that come from MS.

1 comment:

Richard Gillibrand said...

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