What is PLEKHA7 and How It Might be the Cure for Cancer Wonder at long Last #CancerMicroprocesser

Hmm it seems that doctors have found the "cancer microprocesser"

Scientists at the Mayo Clinic in Florida have identified the cell’s microprocessor that controls cell growth. Called microRNA, this biological controller instructs the cells to stop dividing the moment they have replicated sufficiently, The Telegraph reports. When that happens, microRNA triggers the production of a protein called PLEKHA7, which then breaks the cell bonds and stops growth. In cancerous cells, that process doesn’t work properly.

The doctors were able to switch on cancer in cells by removing microRNAs and preventing them from producing the protein. Then they found they can reverse the process, stopping tumor growth and potentially changing cancer growth. All a patient would need would be an injections containing microRNAs that would reinforce the existing supply in cancer cells.

I wonder how these microRNAs effect different kinds of cancer? Are these "cancer microprocessors" different in lung cancer for instance. Also I wonder how much microRNAs are needed to create a stopping and reversing of cancer growth. You could certainly prevent cancer from spreading if you target with different kinds of microRNAs. Very interesting stuff.

McDonalds and Tyson's Teams Move Fast on Chicken Cruelty

They must some 24 hour monitoring going on.

Even by the lightning-fast standards of social media and viral videos, it was enough to make your head spin: No sooner had the activist group Mercy for Animals released a sickening undercover video showing abhorrent treatment of chickens at a Tennessee factory farm that supplies poultry for McDonald’s Chicken McNuggets than both McDonald’s and Tyson Foods, which makes the famed nuggets for the fast-food giant, announced they had severed ties with the offender.

“Based on what we currently know, we are terminating the farmer’s contract to grow chickens for us,” a Tyson spokesman said in a statement. For its part, McDonald’s called the video evidence “unacceptable” and said that the company is “committed to working with animal welfare and industry experts to inform our policies that promote better management, strong employee education and verification practices.”

Trump's Advice is Spot in Regards to the Stock Market Correction. Hold

Yeah sometimes Trump does say something that is not offensive or idiotic.

Donald Trump offered his advice Monday for investors taking a pounding in this week’s market tumble : Don’t sell.

“You’re better off holding,” the former reality show host, real estate scion, and Republican presidential candidate told the New York Times , citing the historical behavior of a crashing market to surge back, allowing those who wait out the storm to avoid losses in the long run.

“I’d hate to see it come back and they end up with the short end of both deals,” he said.

If you have cash wait for the smoke to clear and check if the stock has lots of China exposure and if not then you get to buy it at a discount. 

Time to Buy Google err Alphabet?

Well it seems Google is going to separate the cash cow search business from the pie in the sky stuff and add them both to a holding company called Alphabet. I agree with Cramer when he says this could be huge.

"The problem, though, is that Google has lots of forward-looking projects, truly venture-stage efforts that shouldn't be squelched by Porat, because, with a little nurturing, they could pay off gigantically someday," Cramer said.

The solution? Break them out, just like Amazon did with its Web services division.
Cramer thinks this will allow the huge and fast core business to shine within Alphabet. This way, investors can clearly understand what Google is and why it is worth so much more than anyone thought.

So the money loser (at first) projects can have visibility and don't drag down the core business. You also get a look at these projects while they are being developed and nurtured by looking at the other businesses group that contains Nest, Fiber, the Venture Capital arm, etc. I would love to see what smaller apps that Venture Capital arm is bankrolling to see what could take off. Too bad I couldn't get back in at $550 but 10 shares might become a core holding going forward.

For a Tough New Yorker Trump sure has some Thin Skin. #DumpTrump

I have never seen such a powerful billionaire not be able to any sort of criticism.

“She should really be apologizing to me, you want to know the truth,” Trump said on MSNBC’s “Morning Joe” Monday. “And other candidates have said that.”

During last week’s primetime debate, Kelly, a co-moderator, asked the real estate mogul about his history of sexist comments about women — a question Trump believes was “nasty.”

"It was an inappropriate question,” Trump said on NBC’s “Today” show Monday. “It was a ridiculous question. Even the other candidates came up to me and said that that was absolutely out of line.”

Those are words that came out of his mouth. She used his actual words in context to ask that question. A person who is supposed to be Presidential doesn't call people names and Trump does it all the time. What is funny is that he has to get re-assurances all the time.

On Monday morning, Trump tweeted that he had talked with Fox News chief Roger Ailes, who assured him he would be “treated fairly” by the cable news network.

Oh boo-hoo you haven't been treated "fairl." I guess he just wants a bunch of soft-ball questions and nothing of any substance. Maybe he should run against Hillary instead. I'm sure the Democratic moderators will ask just the questions he wants.

Gasp! I Again Agree With Hillary: Quarterly Capitalism needs to Go: Disney is Case-in-Point

I have to agree with this statement whole-heartedly.

Clinton, the front-running Democratic presidential candidate, said in a speech last month that many important elements of the U.S. economy – publicly traded companies and the executives that run them, shareholders and consumers – are held hostage to the “tyranny of today’s earnings report.”

“Everything is focused on the next earnings report or the short-term share price,” said Clinton. “The result is too little attention on the sources of long-term growth: research and development, physical capital and talent.”

I think one of the big problems with quarterly capitalism is that companies are pressured to buy back shares in order to prop up their stock prices. I'm sure that cash can be plowed back into R&D or simply given as a dividend or a bonus for their employees. Instead that money is used to buy back shares which means a bigger bonus for senior managers with stock options and little else as far as I can see.

You also see big layoffs even though the company has profits because of a bad quarter. The company is still making money but they disappoint Wall Street and 1000s are laid off. Qualcomm comes to mind.

One way of looking at the problem with quarterly capitalism is Disney. I saw an interview with their CEO, Iger which he ticked off like 10 different billion dollar plus movie franchises one after another. Then they will open Shanghai Disneyland which will probably make some of the US Theme parks look like the State Fair. They have all sorts of billion dollar opportunities on the horizon and Iger let us know that.

Instead they have some subscriber slippage at ESPN and the stock drops from $121 to $108 in two days. This doesn't even take into account that Disney will probably offer ESPN as over-the-top service in the coming years and it will still be huge. I would easily pay $20 a month or more in order to watch ESPN on my Roku or Xbox One. It works for HBO so I don't see why it wouldn't work for ESPN which is a channel I watch every day. Quarterly Capitalism thinks that people are cutting the cord and subscribing to Netflix so Disney goes to $0 and Netflix is worth $700 billion. That has to be the most stupid thing ever but the stock market believes that.   

Another View that the Fix is In? Bill Clinton Called Donald Trump before He Decided to Run #DumpTrump

I wonder what Clinton offered him in exchange for putting Hillary in the White House?

Former president Bill Clinton had a private telephone conversation in late spring with Donald Trump at the same time that the billionaire investor and reality-television star was nearing a decision to run for the White House, according to associates of both men.

Four Trump allies and one Clinton associate familiar with the exchange said that Clinton encouraged Trump’s efforts to play a larger role in the Republican Party and offered his own views of the political landscape.

If Trump wins the nomination or runs as a third party then Hillary would win the election handily. Now I would be that in tomorrows debate Trump is going to make a giant ass of himself. A crafty false flag attack the like of which we have never witnessed before.

The Telegram that Made Hitler Kill Himself Nearly Forgotten in South Carolina Safe

Now this is quite a historical find.

A treasonous telegram from No. 2 Nazi Hermann Goering to none other than the führer himself.

A message that, along with the advancing Allied troops, helped drive Adolf Hitler to swallow cyanide and shoot himself inside his underground Berlin bunker.

Despite its influence on World War II, however, the memorandum ended up inside a South Carolina safe, nearly forgotten for more than a decade until a college student made it his senior thesis.

On Tuesday, the itinerant but now infamous telegram sold at auction for $55,000.

Now this is a piece of history like Trotsky's Ice Pick or Martin Luther's (the Nazi Official not the Protestant Reformation guy) Wannsee minutes that doomed millions of Jews. At least this telegram is a good thing though and might have positive karma attached to it.   

Intel and Micron Issuing In a Golden Age of Electronics? 3D XPoint (Cross Point) memory Sounds Awesome

Well this sounds like something that could change quite a few things in the coming years.

Imagine an ultra-small form factor PC, for example, that can instantly power up and start off from the exact point it was shut down, with hundreds of gigabytes of high-speed memory, that’s capable of transferring data at many gigabytes or even terabytes per second.  And that the data can be accessed in Nano-second scales. System memory limitation could essentially be eliminated and there would be no latency associated with copying data from a relatively slow storage device into system memory.

The article mentions Big Data like Tableau Software or Splunk using these chips to mine databases in seconds that it takes hours or days to crunch now. They could even do it in real time depending on how the chips perform. A Tableau or Splunk appliance could sit in front of the data store and constantly mine it for information if need be.

Another thing that it would do is allow streaming to go from the bandwidth intensive to device intensive to allow instant streaming of very high HD movies. Your new version of the Xbox or Roku equipped with these Cross Point chips could download 1000s of movies if you want and store everything and have them all instantly at your fingertips. Imagine if all of Netflixes content was on your Roku ready to be accessed from any device at any time nearly instantly.

You can even have someone curate the movie for you (new job opportunity) so you only watch the funny bits of a comedy or the action scenes or whatever. You might even be able to search the movie (or nearly every movie of a certain genre) for a certain line or scene in real time. Hell, you might be able to do that all on your tablet or iPhone 10 if it has a few of these chips in it.

Now This is How You Do a Review of a Bad Movie: Pixels Edition #WorstMovieoftheYear

I knew the movie looked bad but MovieBob confirms it in this awesome review. In some strange way I think terrible movies like this need to be made so it can justify this kind of review.

Apple Watch Looks like a Dismal Failure after the Early Adoption Rush

It seems Apple Watch is not moving the needle at all.

A slew of recent third-party data has not painted too bright of a picture of Apple Watch sales. One of the most stark is research from Slice Intelligence, which noted Fitbit (FIT) devices outsold the Apple Watch in May, selling 850,000 devices, compared to 777,000 Apple Watches sold. There are multiple Fitbit devices--seven in total--compared to just one Apple Watch (albeit in three versions).

So Fitbit is beating out the Apple Watch? It seems that people who use the Fitbit don't really want to see the weather in Cupertino on their wrist and can just pull their phones out of their pocket. Since people rarely use the cell phone for phone calls talking on your wrist lost its novelty. I think wearing a watch for anything other than a piece of status jewelry is kind of dying. It would be interesting to see how many early Apple Watch owners have the thing sitting on their dresser gathering dust.

More Trump Screwups: Gives out Lindsey Graham's Personal Cell Phone Number: Wait Wouldn't that Be Illegal?

You would figure that this latest blunder would be illegal.

In a characteristically rambling speech to reporters in Bluffton, S.C., Trump told the crowd that Graham once called “begging” him to put in a good word with “Fox & Friends,” the Fox News morning show on which the billionaire businessman and “Celebrity Apprentice” host was a frequent guest.

Trump read aloud Graham’s private telephone number from a piece of paper at the podium.

“Maybe it’s an old number,” Trump told his supporters. “I don’t know, give it a shot.”

A call to the phone number by Yahoo News went to Graham’s voice mailbox, which was full.

Isn't Graham a sitting Senator? You would figure his personal cell number would be a guarded deal because it can be used for all sorts of different hacks and such. Oh well, I guess it is time for Graham to get a new cell phone and send a bill to Trump.

The Difference Between Trump and McCain in 1968: It's Pretty Eye-Opening #DumpTrump

This is all you need to read on Trump vs. McCain during the Vietnam War.

“When I graduated from college, I had a net worth of perhaps $200,000,” he said in his 1987 autobiography “Trump: The Art of the Deal,” written with Tony Schwartz. (That’s about $1.4 million in 2015 dollars.) “I had my eye on Manhattan.”

More than 8,000 miles away, John McCain sat in a tiny, squalid North Vietnamese prison cell. The Navy pilot’s body was broken from a plane crash, starvation, botched operations and months of torture.

As Trump was preparing to take Manhattan, McCain was trying to relearn how to walk.

Yup and McCain could have gotten out of Vietnam because his dad was an Admiral and could have gave him a cushy Pentagon job instead of naval aviator. Instead he decided to go and fly airplanes, and got shot down, and was beaten for it.You can go after McCain's record in the Senate if you want but do not go after his record as a POW because that one is exemplary.

Donald Trump Wouldn't Last a Day in the Hanoi Hilton. He would turn Collaborator at the First Beating Threat #POWHeroes

I think Trump is done after this latest stupid outburst.

Donald Trump launched an outrageous assault on the war record of former prisoner of war Sen. John McCain on Saturday — and ended up shooting himself in the foot.

“He’s not a war hero," Trump said dismissively of McCain, who spent more than five years being tortured as a prisoner of war in Vietnam and suffered permanent injuries as a result.

Trump, who received a number of deferments to avoid serving in Vietnam, backtracked slightly after drawing boos.

“He’s a war hero because he was captured. I like people who weren’t captured,” he said, to a mix of laughs and jeers from the several hundred social conservatives gathered at the Family Leadership Summit.

I don't think Trump would last a day in the Hanoi Hilton. He would probably turn into a collaborator and give up US secrets as soon as he was threatened. He needs to drop out of the race today and not have the damage the GOP any further.

A Clinton Plan I Agree With: Tax Breaks for Profit Sharing

I think this is a great idea that would seriously resonate with certain companies.

Her plan would give businesses that offer employees a share of profits a two-year tax credit equal to at least 15 percent of their profit-sharing payments.

If a company took full advantage of Clinton's profit-sharing tax credit, an employee earning $50,000 per year, for instance, could receive $5,000 in added income, and the company in turn would get a $750 tax credit for that worker.

Even if the company offered everyone common shares of their stock it would create a whole new class of investor. Imagine if every barista at Starbucks received a certain amount of shares in their paycheck each quarter and Starbucks got a tax break because of it. Some long time Starbucks workers might be able to have a decent amount of shares and some pretty nice portfolios due to growth at the company. 

Also the idea of shared success would be on the minds of quite a few workers. If they work hard, the stock price rises, and if the stock price rises, they create wealth. This doesn't only apply to the top managers or white collar workers but to everyone at the company. Sounds like a game-changer.

One of these Things is Not Like the Others: Taylor Swift and SuperModel Pals Tower over Lena Dunham

Wow, these girls are all tall and have some serious heels on. Dunham looks kind of emaciated as well. 

I Agree with Scarborough: If GOP Went After Trump on Bigotry they Might Change the Party #DumpTrump

I agree with this statement.

This is a generational opportunity for Republicans, if you have the right person that goes out there -- defends the law first of all -- but at the same time [as he or she is] defending the law, defends Hispanics and people from Mexico, that actually is remembered in the general election in a way that Romney's unfortunate statement about Hispanics was remembered in 2012.

Yeah and they distance themselves from someone who seems to be actively damaging the party. Trump is such a nuisance I think he might have a deal with Hillary that if she wins he gets some kind of reward or kick-back. Maybe a sweetheart deal with the government worth billions or something similar.

A Very Good Question: Why does Europe Want to Keep Greece?

This article is a real interesting think-piece.

It's easy to understand why the Greeks want to stay in the euro: They need the regular infusions of cash from creditors. The attractions for Europe seem much more elusive. Greece is not exactly a stellar export market right now. Tourism and Greek goods would probably be cheaper for Europeans if Greece were to exit. And if they stay in, the best-case scenario is probably that Greece turns into something like southern Italy -- a poor cousin that never seems to develop no matter how much money is funneled into it. The worst-case scenario is that in a couple of months, or a couple of years, they'll be back around the table negotiating yet another round of emergency measures.

Europe has thrown good money after bad three times so far. Why do they think another $80 billion will put Greece back on their feet anytime soon? The austerity measures seem pretty draconian and the Greeks might need to sell their ruins and seaports to put in some fund.

I can understand that the Germans just want to cut Greece loose and take the loss on paper rather then having to pump money endlessly. The whole idea of contagion has been dealt with. It seems that the countries that were bailed out earlier had the loudest voices toward a "Grexit."

I mean if it were because Greece was a great vacation destination they could have been able to afford it on the cheap if the dracma returned. There will be short term pain but in the long run Greece might start to grow again. Kind of like when a person goes bankrupt they have to endure some pain before they don't have that crushing credit card bill to pay every month.

Here is Something America can be Proud of: We have Visited all 9 Planets (Pluto is a planet in my eyes) in the Solar System #PlutoisaPlanet

I'm sure Ariana Grande is not happy about this but as we visit Pluto we have gone 9 for 9 on planetary visits and just completed the set. However, I think we need to go do a Pluto orbiter next because that world sounds pretty nuts.

Researchers said they can't wait to get a look at the close-approach data. Their appetites have been whetted by observations gathered over the past few weeks showing that Pluto and Charon are complex worlds with surprisingly diverse surfaces.

For example, Pluto sports a polar ice cap and a huge, bright, heart-shaped feature, as well as a giant dark patch mission scientists have dubbed "the whale." Charon, for its part, is scored by craters and canyons, and harbors an enigmatic, 200-mile-wide (320 km) dark blotch at its north pole.

I'm certain "the Whale" and the "Dark Spot of Charon" are alien bases where the Grays launch missions into the interior of our solar system.

Maisie Williams Hates Math, is Awesome, and has the Best Yearbook Quote Suggestion Ever!

She is one of the good things about celebrity culture.

Back in June, a young fan named Rachael Wood tweeted at the actress, requesting a quote for her yearbook. She provided no specific guidelines, she just said, "...if you tweet me back I'll make whatever you say my quote." 

"Anyone can be killed," is how the "Game of Thrones" actress responded to the odd request. Clearly, she turned to her Stark blood for inspiration. 

I think that Faceless Man training on Game of Thrones is paying off. This is also funny:

"And then when I went into secondary school, I just … I started to hate maths because of my teachers. And I feel like that['s] what it is for a lot of people. It’s like, sometimes you don’t get along with your teachers and you start to hate the subjects. It was just like totally what happened with me. So, I’d kill all three of my math teachers … But I wouldn’t actually kill anyone. No."

Wait for the backlash from the math teachers of the world. I have to agree though because my math teacher in high school was awful. It goes to show how important some teachers are to the rest of your life.